Article
Impact of neural cell adhesion molecule deletion on regeneration after mouse spinal cord injury.
The European journal of neuroscience - 1 Jul 2016
Saini Vedangana, Loers Gabriele, Kaur Gurcharan, Schachner Melitta, Jakovcevski Igor
Abstract excerpt
The neural cell adhesion molecule (NCAM) plays important functional roles in development of the nervous system. We investigated the influence of a constitutive ablation of NCAM on the outcome of spinal cord injury. Transgenic mice lacking NCAM (NCAM-/-) were subjected to severe compression injury of the lower thoracic spinal cord using wild-type (NCAM+/+) littermates as controls. According to the single-frame...
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