Article
Interspecific DNA-mediated transfer and amplification of a gene specifying a Mr 100,000 human melanoma-associated cell surface glycoprotein.
Cancer research - 1 Mar 1990
Rosenberg C D, Ferrone S, Hamby C V, Mancino V, Graf L H
Abstract excerpt
The gene that encodes the membrane-bound Mr 100,000 human melanoma-associated antigen (MAA) defined by mouse mAb 376.96, a leukocyte and fibroblast interferon-modulated glycoprotein having preferential distribution on melanoma and carcinoma cells, has been transfected into the mouse melanoma cell...
Topics
- Animals
- Antigens, Neoplasm
- Gene Amplification
- Gene Expression Regulation, Neoplastic
- Humans
- Melanoma
- Melanoma-Specific Antigens
- Molecular Weight
- Neoplasm Proteins
- Phenotype
- Transfection
- Tumor Cells, Cultured
