Article
A monoclonal antibody to Lewis lung carcinoma variant H-59 identifies a plasma membrane protein with apparent relevance to lymph node adhesion and metastasis.
Cancer research - 15 Mar 1990
Shestowsky W, Fallavollita L, Brodt P
Abstract excerpt
Tumors H-59 and M-27, two stable metastatic variants of the Lewis lung carcinoma, differ in their ability to disseminate lymphatically. Tumor H-59 metastasizes to the regional lymph nodes regardless of the local site of growth and gives rise to widespread lymphatic dissemination, whereas tumor M-...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Cell Adhesion
- Cell Line
- Female
- Fluorescent Antibody Technique
- Genetic Variation
- Hydrolases
- Lung Neoplasms
- Lymph Nodes
- Lymphatic Metastasis
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Molecular Weight
- Neoplasm Metastasis