Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of hepatocellular carcinoma biomarker, cyclase-associated protein 2 in zebrafish body development and cancer progression.

Experimental cell research - 1 Jan 2013

Effendi Kathryn, Yamazaki Ken, Mori Taisuke, Masugi Yohei, Makino Shinji, Sakamoto Michiie

Abstract excerpt

Cyclase-associated protein 2 (CAP2) is a conserved protein that is found up-regulated in hepatocellular carcinoma (HCC). By using zebrafish, combined with HCC cell lines, we further investigated the role of CAP2. The zebrafish CAP2 sequence was 60% identical to human CAP2 with 77% homology in the C-terminal actin-binding domain, and 58% in the N-terminal cyclase-binding domain. CAP2 expression was observed during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Gene Expression Regulation, Developmental

Share to Gene Knockdown Techniques

Share to Liver Neoplasms

Share to Zebrafish

Share to Zebrafish Proteins

Source

Identifiers

PMID: 23022774
DOI: 10.1016/j.yexcr.2012.09.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of hepatocellular carcinoma biomarker, cyclase-associated protein 2 in zebrafish body development and cancer progression.PMID 23022774Read ↗

Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer CellsSemantic proximity Read ↗

Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer.Semantic proximity Read ↗

Disease association of cyclase-associated protein (CAP): Lessons from gene-targeted mice and human genetic studiesSemantic proximity Read ↗

miRNA mediated downregulation of non-muscle Cyclase associated protein 1 is required for myogenic differentiationSemantic proximity Read ↗

Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy.Semantic proximity Read ↗

The Cytoskeletal Protein Cyclase-Associated Protein 1 (CAP1) in Breast Cancer: Context-Dependent Roles in Both the Invasiveness and Proliferation of Cancer Cells and Underlying Cell SignalsSemantic proximity Read ↗

Macrophage capping protein CapG is a putative oncogene involved in migration and invasiveness in ovarian carcinoma.Semantic proximity Read ↗

Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish.Semantic proximity Read ↗

A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and CirbpbSemantic proximity Read ↗

The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter regionSemantic proximity Read ↗

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.Semantic proximity Read ↗

Cadherin2 (N-cadherin) plays an essential role in zebrafish cardiovascular development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.