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Disease association of cyclase-associated protein (CAP): Lessons from gene-targeted mice and human genetic studies

8 Feb 2022

Abstract excerpt

Cyclase-associated protein (CAP) is an actin binding protein that has been initially described as partner of the adenylyl cyclase in yeast. In all vertebrates and some invertebrate species, two orthologs, named CAP1 and CAP2, have been described. CAP1 and CAP2 are characterized by a similar multidomain structure, but different expression patterns. Several molecular studies clarified the biological function of the...

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PMID: 35150966
DOI: 10.1016/j.ejcb.2022.151207

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