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Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish.

Gene - 20 Jun 2020

Wu Junjie, Lu Chang, Ge Si, Mei Jie, Li Xiaohui, Guo Wenjie

Abstract excerpt

IGF2BPs, a subclass of RNA-binding proteins, regulate cellular differentiation, proliferation and migration during multiple organs development, but their functions in liver development still remain unclear. Here, in this study, whole-mount in situ hybridization showed that igf2bp1 was constantly and stably expressed at early stages of embryo development in zebrafish. Both the morpholino-induced knockdown and...

Topics

Animals
Cell Proliferation
Hepatocytes
Liver
Morpholinos
Organ Size
Phenotype
RNA-Binding Proteins
Zebrafish
Zebrafish Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32240777
DOI: 10.1016/j.gene.2020.144632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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