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Article

Influence of DNA-repair gene variants on the micronucleus frequency in thyroid cancer patients.

Mutation research - 20 Jan 2013

García-Quispes W A, Pastor S, Galofré P, Biarnés F, Castell J, Velázquez A, Marcos R

Abstract excerpt

The role of different DNA-repair genes (OGG1, XRCC1, XRCC2 and XRCC3) on both the spontaneous and the induced frequency of micronuclei (MN) has been studied in the lymphocytes of a group of 114 patients with differentiated thyroid cancer (DTC). Induction of MN was achieved by treatment of the lymphocytes with 0.5Gy of gamma-radiation. The selected genes are involved in base-excision repair (BER) (OGG1, Ser326Cys;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23022340
DOI: 10.1016/j.mrgentox.2012.08.008

Genes

OGG1
XRCC1
XRCC2
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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