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Article

Basal and induced micronucleus frequencies in human lymphocytes with different GST and NAT2 genetic backgrounds.

Mutation research - 14 Jul 2006

Hernández Alba, Xamena Noel, Gutiérrez Sara, Velázquez Antonia, Creus Amadeu, Surrallés Jordi, Galofré Pere, Marcos Ricardo

Abstract excerpt

Basal and induced frequencies of genetic damage can be modulated by different host factors, including genes involved in phase II metabolism. Since polymorphic variants in the glutathione S-transferase (GST) and N-acetyl transferase (NAT) genes have been associated with cancer risk, we explored the possible links between GSTM1, GSTP1, GSTT1 and NAT2 variants and the frequency of micronuclei (MN) in human...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16621679
DOI: 10.1016/j.mrgentox.2006.02.002

Genes

NAT2
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Basal and induced micronucleus frequencies in human lymphocytes with different GST and NAT2 genetic backgrounds.PMID 16621679Read ↗

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Role of the N-acetyltransferase 2 detoxification system in thyroid cancer susceptibility.Semantic proximity Read ↗

Influence of DNA-repair gene variants on the micronucleus frequency in thyroid cancer patients.Semantic proximity Read ↗

Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers.Semantic proximity Read ↗

GSTT1 and M1 polymorphisms in Hürthle thyroid cancer patients.Semantic proximity Read ↗

Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes.Semantic proximity Read ↗

Chromosomal aberrations under basal conditions and after treatment with X-ray in human lymphocytes as related to the GSTM1 genotype.Semantic proximity Read ↗

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Combined effects of glutathione S-transferase polymorphisms and thyroid cancer risk.Semantic proximity Read ↗

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