Article
Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis.
Thyroid : official journal of the American Thyroid Association - 1 Feb 2009
Ho Tang, Li Guojun, Lu Jiachun, Zhao Chong, Wei Qingyi, Sturgis Erich M
Abstract excerpt
BACKGROUND: Numerous single-nucleotide polymorphisms (SNPs) of the DNA repair gene XRCC1 have been described. These SNPs have been increasingly studied in the epidemiology of various cancer types. In this study we evaluated the risk association between six common SNPs of the XRCC1 gene and differentiated thyroid carcinoma (DTC). METHODS: We conducted a case-control study of 251 subjects with DTC, 145 subjects...
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