The heritability of Dupuytren's disease: familial aggregation and its clinical significance.

doi:10.1016/j.jhsa.2005.09.018

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The heritability of Dupuytren's disease: familial aggregation and its clinical significance.

The Journal of hand surgery - 1 Feb 2006

Hindocha Sandip, John Sally, Stanley John K, Watson Stewart J, Bayat Ardeshir

Abstract excerpt

PURPOSE: Dupuytren's disease (DD) is a benign, fibroproliferative disease affecting the hands. The familial occurrence of DD and its presence in identical twins suggests a genetic basis for the condition. Our aims in this study were (1) to provide evidence for familial aggregation of DD by estimating the sibling recurrence-risk ratio and (2) to link previously associated environmental risk factors with family...

Topics

Adult
Age of Onset
Aged
Aged, 80 and over
Cohort Studies
Cross-Sectional Studies
Dupuytren Contracture
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Recurrence
Risk Factors
Severity of Illness Index
Siblings
Surveys and Questionnaires

Source

Open in PubMed

Identifiers

PMID: 16473680
DOI: 10.1016/j.jhsa.2005.09.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics