Article
Allele-specific transcriptional activity of the variable number of tandem repeats in 5' region of the DRD4 gene is stimulus specific in human neuronal cells.
Genes, brain, and behavior - 1 Mar 2013
Paredes U M, Quinn J P, D'Souza U M
Abstract excerpt
The dopamine receptor D4 (DRD4) gene includes several variable number of tandem repeat loci that have been suggested to modulate DRD4 gene expression patterns. Previous studies showed differential basal activity of the two most common variants of a tandem repeat (120 bp per repeat unit) located in the 5' region adjacent to the DRD4 promoter in human cell lines. In this communication, we further characterized the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
