Tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4).

doi:10.1002/(sici)1096-8628(19991215)88:6<705::aid-ajmg22>3.0.co;2-f

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Article

Tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4).

American journal of medical genetics - 15 Dec 1999

Seaman M I, Fisher J B, Chang F, Kidd K K

Abstract excerpt

The dopamine D4 receptor (DRD4) is a member of the D2-like dopamine receptor family. Polymorphisms at the DRD4 gene have been examined for association with a wide range of neuropsychiatric disorders and normal behavioral variation. The DRD4 gene is unusual in its high amount of expressed polymorphism in humans. Here we study the identification of a polymorphic tandem duplication of 120 bp located 1.2 kb upstream...

Topics

Alleles
Animals
Codon, Initiator
Consensus Sequence
Databases, Factual
Evolution, Molecular
Gene Frequency
Genetic Variation
Gorilla gorilla
Humans
Pan troglodytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Pongo pygmaeus

Receptors, Dopamine D2

Receptors, Dopamine D4

Response Elements

Sequence Homology, Nucleic Acid

Tandem Repeat Sequences

Source

Open in PubMed

Identifiers

PMID: 10581493
DOI: 10.1002/(sici)1096-8628(19991215)88:6<705::aid-ajmg22>3.0.co;2-f

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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