Article
No direct effect of the -521 C/T polymorphism in the human dopamine D4 receptor gene promoter on transcriptional activity.
BMC molecular biology - 24 May 2006
Kereszturi Eva, Kiraly Orsolya, Barta Csaba, Molnar Noemi, Sasvari-Szekely Maria, Csapo Zsolt
Abstract excerpt
BACKGROUND: The human dopamine D4 receptor (DRD4) gene has been studied extensively as a candidate gene for certain psychological traits and several behavioural and psychiatric disorders. Both the 5' regulatory region and the coding sequence contain a number of polymorphisms. The promoter variants have received particular attention in the past few years due to their possible role in the regulation of gene...
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