Article
Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2015
Yin Kai, You Yong, Swier Vicki, Tang Lin, Radwan Mohamed M, Pandya Amit N, Agrawal Devendra K
Abstract excerpt
OBJECTIVE: Prevalence of vitamin D (VD) deficiency and its association with the risk of cardiovascular disease prompted us to evaluate the effect of VD status on lipid metabolism and atherosclerosis in hypercholesterolemic microswine. APPROACH AND RESULTS: Yucatan microswine were fed with VD-deficient (0 IU/d), VD-sufficient (1000 IU/d), or VD-supplemented (3000 IU/d) high-cholesterol diet for 48 weeks. Serum...
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