Article
CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease.
Cardiovascular research - 1 Mar 2018
Verweij Simone L, Duivenvoorden Raphaël, Stiekema Lotte C A, Nurmohamed Nick S, van der Valk Fleur M, Versloot Miranda, Verberne Hein J, Stroes Erik S G, Nahrendorf Matthias, Bekkering Siroon, Bernelot Moens Sophie J
Abstract excerpt
AIMS: Circulating monocytes infiltrate the plaque and differentiate into macrophages, contributing to an inflammatory environment which is associated with higher risk of cardiovascular events. Although the pivotal role of circulating monocytes in plaque inflammation has been firmly established, the search continues to identify specific monocyte subsets that may be especially atherogenic. Therefore, we evaluated...
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