Article
M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetes.
Diabetes & vascular disease research - 1 Jul 2015
Roma-Lavisse Charlotte, Tagzirt Madjid, Zawadzki Christophe, Lorenzi Rodrigo, Vincentelli André, Haulon Stephan, Juthier Francis, Rauch Antoine, Corseaux Delphine, Staels Bart, Jude Brigitte, Van Belle Eric, Susen Sophie, Chinetti-Gbaguidi Giulia, Dupont Annabelle
Abstract excerpt
This study aimed to investigate atherosclerotic mediators' expression levels in M1 and M2 macrophages and to focus on the influence of diabetes on M1/M2 profiles. Macrophages from 36 atherosclerotic patients (19 diabetics and 17 non-diabetics) were cultured with interleukin-1β (IL-1β) or IL-4 to...
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