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Article

HLA-G*0105N null allele encodes functional HLA-G isoforms.

Biology of reproduction - 1 Aug 2005

Le Discorde Magali, Le Danff Caroline, Moreau Philippe, Rouas-Freiss Nathalie, Carosella Edgardo D

Abstract excerpt

Expression of the nonclassical HLA class I antigen, HLA-G, is associated with immune tolerance in view of its role in maintaining the fetus in utero, allowing tumor escape, and favoring graft acceptance. Expressed on invasive trophoblast cells, HLA-G molecules bind inhibitory receptors on maternal T lymphocytes and NK cells, thereby blocking their cytolytic activities and protecting the fetus from maternal immune...

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Identifiers

PMID: 15814900
DOI: 10.1095/biolreprod.104.037986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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