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Article

Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.

Neuroscience letters - 30 Nov 2012

Multani Pushpinder K, Clarke Toni-Kim, Narasimhan Sneha, Ambrose-Lanci Lisa, Kampman Kyle M, Pettinati Helen M, Oslin David W, O'Brien Charles P, Berrettini Wade H, Lohoff Falk W

Abstract excerpt

Genes involved in drug reward pathways are plausible candidates for susceptibility to substance use disorders. Given the prominent role of dopamine in drug reward, dopamine receptor-interacting proteins (DRIPs) such as the neuronal calcium sensor-1 (NCS-1) protein have been hypothesized to play a role in the pathophysiology of cocaine addiction (CA). In this study, we investigated whether genetic variants in the...

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Identifiers

PMID: 22999924
DOI: 10.1016/j.neulet.2012.09.014
PMCID: PMC3895491

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