Article
Genome-wide association study of stimulant dependence.
Translational psychiatry - 29 Jun 2021
Cox Jiayi, Sherva Richard, Wetherill Leah, Foroud Tatiana, Edenberg Howard J, Kranzler Henry R, Gelernter Joel, Farrer Lindsay A
Abstract excerpt
Stimulant dependence is heritable, but specific genetic factors underlying the trait have not been identified. A genome-wide association study for stimulant dependence was performed in a discovery cohort of African- (AA) and European-ancestry (EA) subjects ascertained for genetic studies of alcohol, opioid, and cocaine use disorders. The sample comprised individuals with DSM-IV stimulant dependence (393 EA cases,...
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