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Article

A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 19 Sept 2012

Peng Changgeng, Li Na, Ng Yen-Kar, Zhang Jingzhong, Meier Florian, Theis Fabian J, Merkenschlager Matthias, Chen Wei, Wurst Wolfgang, Prakash Nilima

Abstract excerpt

MicroRNAs have emerged as key posttranscriptional regulators of gene expression during vertebrate development. We show that the miR-200 family plays a crucial role for the proper generation and survival of ventral neuronal populations in the murine midbrain/hindbrain region, including midbrain do...

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Identifiers

PMID: 22993445
DOI: 10.1523/JNEUROSCI.2124-12.2012
PMCID: PMC3752087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22993445-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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