Article
MicroRNA-9 reveals regional diversity of neural progenitors along the anterior-posterior axis.
Developmental cell - 18 Jan 2011
Bonev Boyan, Pisco Angela, Papalopulu Nancy
Abstract excerpt
Neural progenitors self-renew and generate neurons throughout the central nervous system. Here, we uncover an unexpected regional specificity in the properties of neural progenitor cells, revealed by the function of a microRNA--miR-9. miR-9 is expressed in neural progenitors, and its knockdown results in an inhibition of neurogenesis along the anterior-posterior axis. However, the underlying mechanism differs--in...
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