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Article

Regulation of Sox2 by STAT3 Initiates Commitment to the Neural Precursor Cell Fate

1 Apr 2008

Abstract excerpt

STAT3, a member of the signal transducer and activator or transcription (STAT) family of proteins, plays a major role in gliogenesis; however, its functions during differentiation of neural precursor cells (NPCs) are unclear. Our data demonstrate that STAT3 is present and active in the developing mouse central nervous system (CNS) as early as E7.5, several days prior to gliogenesis. We hypothesize that STAT3 is...

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Identifiers

PMID: 18447642
DOI: 10.1089/scd.2007.0098

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