Article
The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Acta neuropathologica - 1 Nov 2012
Collins Mahlon, Riascos David, Kovalik Tina, An Jiyan, Krupa Kelly, Krupa Kristin, Hood Brian L, Conrads Thomas P, Renton Alan E, Traynor Bryan J, Bowser Robert
Abstract excerpt
RNA-binding protein pathology now represents one of the best characterized pathologic features of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration patients with TDP-43 or FUS pathology (FTLD-TDP and FTLD-FUS). Using liquid chromatography tandem mass spectrometry, we ident...
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