Article
Deep sequencing does not reveal additional transmitted mutations in patients diagnosed with HIV-1 variants with single nucleoside reverse transcriptase inhibitor resistance mutations.
HIV medicine - 1 Mar 2013
Pingen M, van der Ende M E, Wensing A M, el Barzouhi A, Simen B B, Schutten M, Boucher C A B
Abstract excerpt
OBJECTIVES: The aim of the study was to gain more insight into the relationship between transmitted singletons found at HIV diagnosis by population sequencing and the possible presence of clinically relevant viral minorities containing additional resistance mutations. METHODS: We studied the viral quasispecies and therapy response in 10 individuals with transmitted single nucleoside reverse transcriptase...
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