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Article

Inferred spoligoforest topology unravels spatially bimodal distribution of mutations in the DR region.

IEEE transactions on nanobioscience - 1 Sept 2012

Ozcaglar Cagri, Shabbeer Amina, Kurepina Natalia, Rastogi Nalin, Yener Bülent, Bennett Kristin P

Abstract excerpt

Biomarkers of Mycobacterium tuberculosis complex (MTBC) mutate over time. Among the biomarkers of MTBC, spacer oligonucleotide type (spoligotype) and mycobacterium interspersed repetitive unit (MIRU) patterns are commonly used to genotype clinical MTBC strains. In this study, we present an evolution model of spoligotype rearrangements using MIRU patterns to disambiguate the ancestors of spoligotypes. We use a...

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PMID: 22987125
DOI: 10.1109/TNB.2012.2213265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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