Article
Mycobacterium tuberculosis spoligotypes that may derive from mixed strain infections are revealed by a novel computational approach.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2012
Lazzarini Luiz Claudio O, Rosenfeld Jeffrey, Huard Richard C, Hill Véronique, Lapa e Silva José Roberto, DeSalle Rob, Rastogi Nalin, Ho John L
Abstract excerpt
Global control of tuberculosis is increasingly dependent on rapid and accurate genetic typing of Mycobacteriumtuberculosis. Spoligotyping is a first-line genotypic fingerprinting method for M.tuberculosis isolates. An international online database (SpolDB4) of spoligotype patterns has been established wherein a clustered pattern (shared by ≥2 isolates) is designated a shared international type (SIT). Dual...
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