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Article

MLVA based classification of Mycobacterium tuberculosis complex lineages for a robust phylogeographic snapshot of its worldwide molecular diversity.

PloS one - 1 Jan 2012

Hill Véronique, Zozio Thierry, Sadikalay Syndia, Viegas Sofia, Streit Elisabeth, Kallenius Gunilla, Rastogi Nalin

Abstract excerpt

Multiple-locus variable-number tandem repeat analysis (MLVA) is useful to establish transmission routes and sources of infections for various microorganisms including Mycobacterium tuberculosis complex (MTC). The recently released SITVITWEB database contains 12-loci Mycobacterial Interspersed Repetitive Units--Variable Number of Tandem DNA Repeats (MIRU-VNTR) profiles and spoligotype patterns for thousands of MTC...

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PMID: 22984400
DOI: 10.1371/journal.pone.0041991
PMCID: PMC3439451

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