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Article

Contribution of rs11465788 in IL23R gene to Crohn's disease susceptibility and phenotype in Chinese population.

Journal of genetics - 1 Aug 2009

Bin Chen, Zhirong Zeng, Xiaoqin Wu, Minhu Chen, Mei Li, Xiang Gao, Baili Chen, Pinjin Hu

Abstract excerpt

Multiple studies have shown that IL23 cytokine plays an essential role in the development of autoimmune diseases by activating IL17-producing helper T (Th17) cells. Given that the susceptibility loci in IL23R for Crohn's disease (CD) is present in Western population and not in Asian population; we screened the IL23R gene by DNA sequencing to identify susceptibility loci in a selected CD cohort and confirmed it in...

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PMID: 19700857
DOI: 10.1007/s12041-009-0027-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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