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Article

Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype.

The Journal of biological chemistry - 26 Oct 2012

Kim Choonkeun, Milheiriço Catarina, Gardete Susana, Holmes Mark A, Holden Matt T G, de Lencastre Hermínia, Tomasz Alexander

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA) strains show strain-to-strain variation in resistance level, in genetic background, and also in the structure of the chromosomal cassette (SCCmec) that carries the resistance gene mecA. In contrast, strain-to-strain variation in the sequence of the mecA determinant was found to be much more limited among MRSA isolates examined so far. The first exception to this...

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Aminoacyltransferases
beta-Lactam Resistance
Boron Compounds
Cefoxitin
Inhibitory Concentration 50

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Penicillin-Binding Proteins

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PMID: 22977239
DOI: 10.1074/jbc.M112.395962
PMCID: PMC3481288

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Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype.PMID 22977239Read ↗

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