Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G/A polymorphism in intronic sequence affects the processing of MAO-B gene in patients with Parkinson disease.

FEBS letters - 19 Oct 2012

Jakubauskiene Egle, Janaviciute Valda, Peciuliene Inga, Söderkvist Peter, Kanopka Arvydas

Abstract excerpt

Monoamine oxidase B (MAO-B) plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Increased levels of MAO-B mRNA and enzymatic activity have been reported in platelets from patients with Parkinson's and Alzheimer's diseases, however the triggers of enhanced mRNA levels are unknown. Our results demonstrate for the first time that G/A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biomarkers
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Introns

Share to Monoamine Oxidase

Share to Parkinson Disease

Share to RNA Precursors

Share to RNA Splicing

Source

Identifiers

PMID: 22974659
DOI: 10.1016/j.febslet.2012.08.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G/A polymorphism in intronic sequence affects the processing of MAO-B gene in patients with Parkinson disease.PMID 22974659Read ↗

DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls.Semantic proximity Read ↗

Platelet monoamine oxidase activity is related to MAOB intron 13 genotype.Semantic proximity Read ↗

Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease.Semantic proximity Read ↗

Variations in the monoamine oxidase B lpar;MAOB) gene are associated with Parkinson's diseaseSemantic proximity Read ↗

A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease.Semantic proximity Read ↗

The lack of association between monoamine oxidase (MAO) intron 13 polymorphism and platelet MAO-B activity among men.Semantic proximity Read ↗

Association analysis of a polymorphism of the monoamine oxidase B gene with Parkinson's disease in a Japanese population.Semantic proximity Read ↗

Monoamine oxidase B polymorphism, cigarette smoking and risk of Parkinson's disease: a study in an Asian population.Semantic proximity Read ↗

Human monoamine oxidase A and B genes exhibit identical exon-intron organization.Semantic proximity Read ↗

A meta-analysis on relationship of MAOB intron 13 polymorphisms, interactions with smoking/COMT H158L polymorphisms with the risk of PD.Semantic proximity Read ↗

An allelic association study of monoamine oxidase B in parkinson's diseaseSemantic proximity Read ↗

The monoamine oxidase B gene GT repeat polymorphism and Parkinson's disease in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.