Article
Platelet monoamine oxidase activity is related to MAOB intron 13 genotype.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2000
Garpenstrand H, Ekblom J, Forslund K, Rylander G, Oreland L
Abstract excerpt
Monoamine oxidases (MAO) play a critical role in the degradation of endogenous and exogenous amines throughout the body. There are two distinct MAO isoforms, MAO-A and MAO-B, which both are encoded in genes on the X chromosome. Alterations in MAO-B activity have previously been connected with several neurological disorders. Platelet MAO (trbc-MAO) is exclusively of the B-type and the catalytic activity of this...
Topics
- Adult
- Analysis of Variance
- Blood Platelets
- Genotype
- Humans
- Introns
- Male
- Monoamine Oxidase
- Polymorphism, Genetic
