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Article

A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease.

Neurology - 1 May 1998

Checkoway H, Franklin G M, Costa-Mallen P, Smith-Weller T, Dilley J, Swanson P D, Costa L G

Abstract excerpt

In a population-based case-control study, we found a reversal of the association of cigarette smoking with Parkinson's disease (PD) in relation to the monoamine oxidase B intron 13 genetic polymorphism. A reduced PD risk related to pack-years of smoking was detected for persons with the G allele, whereas an opposite effect was found among persons with the A allele. These results indicate an unexplained...

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Identifiers

PMID: 9596006
DOI: 10.1212/wnl.50.5.1458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease.PMID 9596006Read ↗

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Genetic polymorphism of dopamine D2 receptors in Parkinson's disease and interactions with cigarette smoking and MAO-B intron 13 polymorphism.Semantic proximity Read ↗

G/A polymorphism in intronic sequence affects the processing of MAO-B gene in patients with Parkinson disease.Semantic proximity Read ↗

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