Article
Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease.
American journal of medical genetics - 18 Apr 1997
Costa P, Checkoway H, Levy D, Smith-Weller T, Franklin G M, Swanson P D, Costa L G
Abstract excerpt
Monoamine oxidase B (MAO-B) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron 13 of...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Female
- Genotype
- Humans
- Introns
- Male
- Middle Aged
- Monoamine Oxidase
- Parkinson Disease
- Polymorphism, Genetic
