Article
The monoamine oxidase B gene GT repeat polymorphism and Parkinson's disease in a Chinese population.
Journal of neurology - 1 Jan 2000
Mellick G D, Buchanan D D, Silburn P A, Chan D K, Le Couteur D G, Law L K, Woo J, Pang C P
Abstract excerpt
Monoamine oxidase B (MAOB) metabolises dopamine and activates neurotoxins known to induce parkinsonism in humans and primates. Therefore the MAOB gene (MAOB; Xp15.21-4) is a candidate gene for Parkinson's disease (PD). Longer length dinucleotide repeat sequences in a highly polymorphic GT repeat region of intron 2 of this gene showed an association with PD in an Australian cohort. We repeated this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
