Article
Association analysis of a polymorphism of the monoamine oxidase B gene with Parkinson's disease in a Japanese population.
American journal of medical genetics - 18 Dec 1995
Morimoto Y, Murayama N, Kuwano A, Kondo I, Yamashita Y, Mizuno Y
Abstract excerpt
The polymorphic allele of the monoamine oxidase B (MAO-B) gene detected by polymerase chain reaction (PCR) and single-stranded conformation polymorphism (SSCP) was associated with Parkinson's disease (PD) in Caucasians. We characterized this polymorphic allele, allele 1, of the MAO-B gene using d...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- DNA Primers
- Female
- Gene Frequency
- Humans
- Introns
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Monoamine Oxidase
- Parkinson Disease
- Point Mutation
- Polymorphism, Genetic