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Article

Induction of cancerous stem cells during embryonic stem cell differentiation.

The Journal of biological chemistry - 26 Oct 2012

Fujimori Hiroaki, Shikanai Mima, Teraoka Hirobumi, Masutani Mitsuko, Yoshioka Ken-ichi

Abstract excerpt

Stem cell maintenance depends on their surrounding microenvironment, and aberrancies in the environment have been associated with tumorigenesis. However, it remains to be elucidated whether an environmental aberrancy can act as a carcinogenic stress for cellular transformation of differentiating...

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Identifiers

PMID: 22961983
DOI: 10.1074/jbc.M112.372557
PMCID: PMC3481281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22961983-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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