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Metabolic and epigenetic reprogramming in the arsenic-induced cancer stem cells

19 Apr 2019

Abstract excerpt

At present, the belief that genetic mutations control every aspect of tumorigenesis is still very popular. Even for the highly debated "bad luck" theory of cancers, it ascertained that random mutation of genes during the self-renewal of somatic stem cells is responsible for cancer initiation. Logically, most of the new therapeutic strategies so far, from molecular targeting to precision medicine or personalized...

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PMID: 31009762
DOI: 10.1016/j.semcancer.2019.04.003

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