Article
Prokineticin 2 is involved in the thermoregulation and energy expenditure.
Regulatory peptides - 10 Nov 2012
Zhou Wenbai, Li Jia-Da, Hu Wang-Ping, Cheng Michelle Y, Zhou Qun-Yong
Abstract excerpt
Animals have developed adaptive strategies to survive tough situations such as food shortage. However, the underlying molecular mechanism is not fully understood. Here, we provided evidence that the regulatory peptide prokineticin 2 (PK2) played an important role in such an adaptation. The PK2 expression was rapidly induced in the hypothalamic paraventricular nucleus (PVN) after fasting, which can be mimicked by...
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