Article
Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males.
Bone - 1 Dec 2012
Han Yingying, Pei Yufang, Liu Yaozhong, Zhang Lei, Wu Shuyan, Tian Qing, Chen Xiangding, Shen Hui, Zhu Xuezhen, Papasian Christopher J, Deng Hongwen
Abstract excerpt
Compressive strength index (CSI) is a newly established index for predicting hip fracture, the most serious consequence of osteoporosis. Appendicular lean mass (ALM), which influences skeletal strength of the lower limbs, is another trait associated with the risk of hip fracture. In this study, we performed a bivariate genome-wide association study (GWAS) to identify new candidate genes responsible for both CSI...
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