Article
Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012
Bilokapic Silvija, Schwartz Thomas U
Abstract excerpt
Nucleocytoplasmic transport is mediated by nuclear pore complexes (NPCs), enormous assemblies composed of multiple copies of ~30 different proteins called nucleoporins. To unravel the basic scaffold underlying the NPC, we have characterized the species-specific scaffold nucleoporin Nup37 and ELY5/ELYS. Both proteins integrate directly via Nup120/160 into the universally conserved heptameric Y-complex, the...
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