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Article

Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex.

Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009

Seo Hyuk-Soo, Ma Yingli, Debler Erik W, Wacker Daniel, Kutik Stephan, Blobel Günter, Hoelz André

Abstract excerpt

The Nup84 complex constitutes a key building block in the nuclear pore complex (NPC). Here we present the crystal structure of one of its 7 components, Nup120, which reveals a beta propeller and an alpha-helical domain representing a novel fold. We discovered a previously unidentified interaction of Nup120 with Nup133 and confirmed the physiological relevance in vivo. As mapping of the individual components in...

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Identifiers

PMID: 19706512
DOI: 10.1073/pnas.0907453106
PMCID: PMC2732846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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