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Article

Genome hyperevolution and the success of a parasite.

Annals of the New York Academy of Sciences - 1 Sept 2012

Barry J David, Hall James P J, Plenderleith Lindsey

Abstract excerpt

The strategy of antigenic variation is to present a constantly changing population phenotype that enhances parasite transmission, through evasion of immunity arising within, or existing between, host animals. Trypanosome antigenic variation occurs through spontaneous switching among members of a silent archive of many hundreds of variant surface glycoprotein (VSG) antigen genes. As with such contingency systems...

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Identifiers

PMID: 22954210
DOI: 10.1111/j.1749-6632.2012.06654.x
PMCID: PMC3467770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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