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Article

The structure of a membrane fusion mutant of the influenza virus haemagglutinin.

The EMBO journal - 1 Jan 1990

Weis W I, Cusack S C, Brown J H, Daniels R S, Skehel J J, Wiley D C

Abstract excerpt

The haemagglutinin glycoprotein (HA) of influenza virus specifically mediates fusion of the viral and host cell endosomal membranes at the acidic pH of endosomes. The HAs from mutant viruses with raised fusion pH optima contain amino acid substitutions in regions of the HA structure thought to be involved in the fusion process [Daniels et al. (1985b) Cell, 40, 431-439]. We have determined the neutral pH crystal...

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Identifiers

PMID: 2295311
DOI: 10.1002/j.1460-2075.1990.tb08075.x
PMCID: PMC551624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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