Article
Identification of specific histidines as pH sensors in flavivirus membrane fusion.
The Journal of cell biology - 20 Oct 2008
Fritz Richard, Stiasny Karin, Heinz Franz X
Abstract excerpt
The flavivirus membrane fusion machinery, like that of many other enveloped viruses, is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. It has been hypothesized that conserved histidines in the class II fusion protein E of these viruses function as mol...
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