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Article

Allele specific expression in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jun 2026

Wang Zishan, Hossain Delowar, Wang Judy Jiaru, Subramaniam Varun R, Zhang Bin, Wang Minghui, Huang Kuan-Lin

Abstract excerpt

INTRODUCTION: Allele-specific expression (ASE), preferential expression of one allele at a heterozygous locus, is implicated in various brain diseases but remains largely uncharacterized in Alzheimer's disease (AD). METHODS: We performed a genome-wide characterization of ASE variants across seven brain regions of 2,231 AD and Control patients from Mount Sinai Brain Bank (MSBB) and Religious Orders Study/Memory...

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Identifiers

PMID: 42273872
DOI: 10.1002/alz.71558
PMCID: PMC13254825

Genes

APOE
CLU
CTSB
SLC12A5
SYT13
TOMM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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