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Article

The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in <i>Drosophila</i> ovarian follicle cells

6 Sept 2012

Abstract excerpt

DNA replication origin activity changes during development. Chromatin modifications are known to influence the genomic location of origins and the time during S phase that they initiate replication in different cells. However, how chromatin regulates origins in concert with cell differentiation remains poorly understood. Here, we use developmental gene amplification in Drosophila ovarian follicle cells as a model...

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Share to Epigenetics and DNA Methylation
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PMID: 22951641
DOI: 10.1242/dev.083576

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