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Article

Kinetics and thermodynamics of phenotype: unwinding and rewinding the nucleosome.

Journal of molecular biology - 9 Nov 2012

Mack Andrew H, Schlingman Daniel J, Ilagan Robielyn P, Regan Lynne, Mochrie Simon G J

Abstract excerpt

Chromatin "remodeling" is widely accepted as the mechanism that permits access to DNA by the transcription machinery. To date, however, there has been no experimental measurement of the changes in the kinetics and thermodynamics of the DNA-histone octamer association that are required to remodel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22944905
DOI: 10.1016/j.jmb.2012.08.021
PMCID: PMC3902851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22944905-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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