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Article

Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Genes & development - 15 Aug 2002

Saha Anjanabha, Wittmeyer Jacqueline, Cairns Bradley R

Abstract excerpt

Chromatin-remodeling complexes couple ATP hydrolysis to alterations in histone-DNA interactions and nucleosome mobility, allowing transcription factors access to chromatin. Here, we use triple-helix strand-displacement assays, DNA length-dependent ATPase assays, and DNA-minicircle ATPase assays to establish that RSC, as well as its isolated ATPase subunit Sth1, are DNA translocases. RSC/Sth1 ATPase activity is...

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Identifiers

PMID: 12183366
DOI: 10.1101/gad.995002
PMCID: PMC186443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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