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Article

Morphine clearance in children: does race or genetics matter?

Journal of opioid management - 1 Jan 2000

Sadhasivam Senthilkumar, Krekels Elke H J, Chidambaran Vidya, Esslinger Hope R, Ngamprasertwong Pornswan, Zhang Kejian, Fukuda Tsuyoshi, Vinks Alexander A

Abstract excerpt

OBJECTIVE: Interindividual variability in analgesic response and adverse effects of opioids because of narrow therapeutic indices are major clinical problems. Morphine is an opioid commonly used in children to manage perioperative pain. Al-though size and age often are considered primary covariates for morphine pharmacokinetic models, the impact of other factors important in personalizing care such as race and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22941849
DOI: 10.5055/jom.2012.0119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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