Article
Exome RNA sequencing reveals rare and novel alternative transcripts.
Nucleic acids research - 7 Jan 2013
Halvardson Jonatan, Zaghlool Ammar, Feuk Lars
Abstract excerpt
RNA sequencing has become an important method to perform hypothesis-free characterization of global gene expression. One of the limitations of RNA sequencing is that most sequence reads represent highly expressed transcripts, whereas low level transcripts are challenging to detect. To combine the benefits of traditional expression arrays with the advantages of RNA sequencing, we have used whole exome enrichment...
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